Fapreen^® 

Next Generation Sequencing

（For Research Use Only）

BACKGROUND

The mechanism of tumor occurrence and development is very complex. Although a large number of tumor-related genes have been discovered, there are still many unknown areas of gene action mechanisms, and more scientific research is needed to explore them. Large-scale genetic testing can comprehensively and intuitively characterize tumor genome variation, and benefit to discover rare mutations in more key genes of patients.

Through NGS panel detection and matching treatment plans, the overall survival rate of patients is improved, which can provide more treatment opportunities and clinical benefits for patients with advanced tumors.

JCO Precis Oncol. 2019 Mar 8;3:PO.18.00213.

DESIGN IDEA

Tumor Comprehensive Genomic Profiling Panel design idea: 602 tumor-related genes;

Covering two authoritative panels approved by FDA: Foundation One & MSK-IMPACT.

Tumor Comprehensive Genomic Profiling Panel

TESTING CONTENT MODULES

PRODUCT ADVANTAGES

(1)Covers coding regions of hot genes in solid tumors, common fusion-related intronic regions, with a panel size of approximately 2.6Mb.

(2)Detects various types of mutations, including SNV, CNV, InDel, and Fusion.

(3)Covers all FDA/NMPA-approved targeted drugs.

(4)Comprehensive assessment of PD-1/PD-L1 immunotherapy, including MSI, TMB, and positive/negative immune modulation factors.

(5)Regularly updates and maintains the gene drug database.

(6)Offers sustainable upgrades and customizable services to accommodate different research needs.

PRODUCT INFORMATION

Tumor Comprehensive Genomic Profiling Panel Assay includes DNA library construction assay, Tumor Comprehensive Genomic Profiling Panel capture assay and SG Pure Beads .

GENE LIST

OUR SERVICE

Our products are rich and diverse, updated around clinical needs and academic hot spots, covering more than 40 testing services applied to NGS platform, real-time PCR platform, digital PCR platform, nucleic acid mass spectrometry platform, which can be customized into personalized panels according to your needs (target genes/sites/variant forms ).

DETECTION PROCESS 

1.Nucleic Acid Extraction

2.Library Preparation （3.5 hours total time）

3.Sequencing

4.Auto-data Analysis

5.Report