(High Throughput Sequencing)
Research Use Only
It is reported that the side effects of drug reactions are the major cause of global death, ranking at the fourth to sixth. In China, there are 2.5 million people who were hospitalized because of adverse drug reactions per year, 200,000 people died of adverse drug reactions per year. In the United States, 2 million people who were hospitalized because of adverse drug reactions per year, more than 100,000 people died of adverse drug reactions per year.
The diversities of drug metabolic enzymes and pharmacological target genotypes can bring about individual differences in drug responsiveness (including drug efficacy and adverse drug reaction) through influencing the concentration of the drug in vivo, and the sensitivity of the target tissue to the drug. This kit detects 55 SNP sites of 21 pharmacogenomics related genes, which can guide the clinical assessment for selecting appropriate drugs and dosage for individual patients, for achieving personalized medication, improving the effectiveness and safety of drug treatment and preventing the occurrence of serious adverse drug reactions.
|21 Genes||55 Loci|
Applicable for 10 hospital departments
Indications for more than 100 drugs
H L A - A,H L A - B,
F 5, F 2,CYP2D6,
H L A - A * 3 1 0 1,
N A T 2*5,Leiden,
α、β-receptor blocker: Carvedilol,( Carvedilol Tablet)
hypotensor : Benazepril,
(Benazepril Hydrochloride Tablets)antineoplastic drugs: Irinotecan
(Irinotecan Hydrochloride Injection),cyclophosphamide
(Adenosine Cyclphosphate for Injection ,Compound Cyclohosphamide Tablets),
Adriamycin(Doxorubicin Hydrochloride for Injection)and so on
Indications for pharmacogenomics SNP detection (Partial)
(Benazepril Hydrochloride Tablets)
for Injection), Cyclophosphamide( Cyclophosphamide for Injection, CompoundCyclophosphamide Tablets)
Mayhave an increased risk of
(Cyclophosphamide for Injection, Compound Cyclophosphamide
SNP Detection Kit
16 Tests/Kit or
Ion torrent ,
● Direct clinical selection of appropriate drugs and dosage for specific patients.
● Improve the effectiveness and safety of drug treatment and prevent the occurrence of serious adverse drug reactions.
Easy operation: With independent patented RingCap® technology, library construction can be done in two steps.
Rapid Detection: Library construction takes only 3.5 hours.Only 2 working days from sample processing to reporting.
Comprehensive Inspection: This kit can detect 21 target genes, 55 loci in one time, and it can make a comprehensive guidance for specific patients to select the appropriate drug and dosage, for personalized treatment.